Stay Alert for Opioid-Induced Hyperalgesia

You’ll get questions about opioid-induced hyperalgesia...due to a recent FDA warning and opioid label changes.

Opioids can sometimes paradoxically cause increased pain, hyperalgesia...or pain from nonpainful stimuli, allodynia.

Opioid-induced hyperalgesia can happen with a range of opioids. Explain that it’s more likely with higher doses and longer durations, but onset varies...and the exact incidence isn’t known.