Compare Nalmefene and Naloxone for Opioid Overdose Reversal

December 2023

New Rx nalmefene nasal spray (Opvee) will join naloxone as an option to reverse opioid overdose.

Both are opioid receptor blockers...with an onset of 3 to 5 minutes.

But nalmefene nasal spray lasts about 6 hours...versus about 2 hours for naloxone nasal spray.

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Table of Contents

Antihypertensives Answer Common Questions About First-Line BP Meds
Hypertension Use a Conservative Approach for Most Inpatient Hypertension
Naloxone Compare Nalmefene and Naloxone for Opioid Overdose Reversal
Diabetes Navigate Risk of Ketoacidosis Due to an SGLT2 Inhibitor
Cardiology Know the Role of Colchicine for Chronic Coronary Disease
Infectious Diseases Give Guidance About At-Home Tests for Respiratory Viruses
Communication Continue to Reinforce Using Inclusive Language
NatMed Spotlight Be on the Lookout for Interactions With St. John’s Wort