Avoid Clinical Inertia in Patients With HFrEF and CKD

Few patients with chronic kidney disease (CKD) are on optimized meds for heart failure with reduced ejection fraction (HFrEF).

It’s a delicate balance. Hyperkalemia can occur with an ACEI or ARB, Entresto (sacubitril/valsartan), or an aldosterone antagonist.

Plus these meds or SGLT2 inhibitors (Farxiga, etc) can cause an initial bump in serum creatinine (SCr).

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