Set Expectations About PPIs for Treating GERD

You’ll see continued emphasis on optimizing PPIs for gastroesophageal reflux disease (GERD).

PPIs are still the mainstay for severe or frequent GERD symptoms, such as heartburn or regurgitation 2 or more times/week.

Start with a standard-dose PPI (omeprazole 20 mg, etc) once daily 30 to 60 min before the first meal of the day...since PPIs inhibit active proton pumps.

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