kidney problems when clarithromycin is combined with a calcium channel blocker (amlodipine, etc)
January 2014
You'll get alerts about kidney problems when clarithromycin is combined with a calcium channel blocker (amlodipine, etc).
Clarithromycin is a strong 3A4 inhibitor that can slow the metabolism of calcium channel blockers and increase their levels.
This can lead to hypotension...edema...bradycardia...and acute kidney injury due to reduced perfusion.
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